Best Compounded Semaglutide Pharmacies (2025)

With brand-name Wegovy costing $1,349+ per month and Ozempic at $968+, many people are turning to compounded semaglutide as an affordable alternative. But not all compounding pharmacies are equal. Here's how to identify the safest options.

How We Evaluated Providers

We assessed each telehealth provider across five key criteria that directly impact safety and value:

• Pharmacy Type (503A vs 503B): 503B outsourcing facilities follow FDA cGMP standards and provide an additional layer of oversight
• Safety Certifications: LegitScript certification and PCAB accreditation indicate higher quality standards
• Regulatory Record: Whether the provider has received FDA warning letters or FTC actions
• Pricing Transparency: Clear disclosure of all costs including consultations, shipping, and supplies
• Consumer Feedback: BBB ratings and accreditation status

Top Compounded Semaglutide Providers

Based on our analysis, here are the providers that stood out for their safety certifications, transparency, and clean regulatory records:

Best for Safety Certifications: MEDVi

MEDVi has built a strong reputation by partnering with established compounding pharmacies and maintaining transparent pricing. They offer both injectable and oral tablet forms of compounded semaglutide, giving patients options based on their preferences.

Best for Pharmacy Transparency: Henry Meds

Henry Meds is one of the few providers that explicitly discloses using both 503A and 503B compounding facilities. This transparency about pharmacy sourcing is relatively rare in the industry and helps patients make informed decisions.

Largest Platform: Hims & Hers

Hims & Hers is the largest player in this space and a publicly-traded company. They offer both compounded and brand-name GLP-1 options. However, they received an FDA warning letter in September 2025 for claims that their compounded products were "FDA-approved" – which is false for any compounded medication.

Despite the regulatory issue, Hims maintains an A+ BBB rating, suggesting they have effective customer service operations. The FDA warning relates to marketing claims rather than product quality, but it's still a factor to consider.

Providers to Approach with Caution

Our research identified several providers with concerning signals that warrant extra due diligence:

ReflexMD

BMIMD

Sprout Health

What to Look For When Choosing

When evaluating any compounded semaglutide provider, prioritize these factors:

1. Pharmacy Type Disclosure

The best providers clearly state whether they use 503A or 503B compounding facilities. 503B outsourcing facilities are FDA-registered and follow cGMP standards, providing additional oversight. If a provider won't disclose their pharmacy type, that's a red flag.

2. LegitScript Certification

LegitScript is a third-party verification service that screens telehealth pharmacies. Certification indicates the provider meets legitimate business standards. You can verify any provider's status at legitscript.com.

3. PCAB Accreditation

The Pharmacy Compounding Accreditation Board (PCAB) accredits compounding pharmacies that meet rigorous quality standards. Only about 8% of the 7,500+ compounding pharmacies in the U.S. hold this accreditation. Ask whether the provider's pharmacy partner is PCAB-accredited.

4. Transparent Pricing

Look for providers that clearly disclose all costs upfront, including medication, consultation fees, shipping, and supplies. Be wary of providers that require you to complete a consultation before revealing pricing.

5. Clean Regulatory Record

Check whether the provider has received FDA warning letters or FTC actions. While a warning letter doesn't necessarily mean the product is unsafe, it indicates the company has made misleading claims in their marketing.

Pricing Comparison

Compounded semaglutide typically costs between $149-350 per month, compared to $968+ for brand-name Ozempic or $1,349+ for Wegovy. Here's how the major providers compare:

The Bottom Line

When choosing a compounded semaglutide provider, prioritize safety certifications over the lowest price. Providers like MEDVi and Henry Meds offer transparency about their pharmacy sourcing and hold third-party certifications that indicate higher quality standards.

Be cautious of providers with undisclosed pricing, vague pharmacy information, or poor BBB ratings. The savings aren't worth the risk if you can't verify the quality and legitimacy of what you're receiving.