Is Compounded GLP-1 Legal in Florida? (2025)

Good news for Florida residents: compounded GLP-1 medications like semaglutide and tirzepatide are legal in the Sunshine State. Most major telehealth providers ship to Florida, and the state has a well-established regulatory framework for compounding pharmacies. Here's what you need to know.

The Short Answer

Yes, compounded GLP-1 medications are legal in Florida. Residents can obtain compounded semaglutide and tirzepatide through telehealth consultations with licensed providers. Florida's regulations allow both in-state compounding pharmacies and properly registered out-of-state pharmacies to ship sterile compounded medications to patients.

Florida is one of the more accessible states for compounded GLP-1 access. Unlike some states with stricter telehealth or compounding regulations, Florida has clear pathways for patients to receive these medications legally.

Florida's Compounding Pharmacy Regulations

Florida's Board of Pharmacy regulates compounding activities under Chapter 465 of the Florida Statutes and Rule 64B16-27 of the Florida Administrative Code. The state has established specific requirements for both sterile and non-sterile compounding.

For sterile products like injectable semaglutide and tirzepatide, Florida requires pharmacies to obtain a Special Sterile Compounding Permit. This permit ensures pharmacies meet USP Chapter 797 standards for sterile preparation, which includes requirements for cleanrooms, environmental monitoring, and personnel training.

Key Florida Requirements

The Florida Board of Pharmacy mandates that all sterile compounding must be performed in accordance with USP Chapter 797 standards, which took effect in November 2023. Pharmacies must maintain proper cleanroom environments, conduct environmental monitoring, and ensure staff are adequately trained in aseptic technique.

For out-of-state pharmacies shipping to Florida patients, the state requires a Nonresident Sterile Compounding Permit under Section 465.0158 of the Florida Statutes. This means any telehealth provider shipping compounded GLP-1s to Florida must work with pharmacies that hold this specific permit.

Telehealth Regulations in Florida

Florida has embraced telehealth, particularly following the COVID-19 pandemic. The state allows licensed physicians to prescribe controlled and non-controlled substances via telehealth consultations, including GLP-1 medications.

For a telehealth prescription to be valid in Florida, the prescribing provider must be licensed in the state or hold an appropriate telemedicine license. Many national telehealth companies maintain Florida-licensed providers specifically for this purpose.

Florida does not require an initial in-person visit before prescribing most medications via telehealth, which makes it easier for residents to access GLP-1 therapy without visiting a physical clinic.

Which Providers Ship to Florida?

The majority of national telehealth GLP-1 providers serve Florida residents. Based on our research, here are some of the major providers and their Florida availability:

Note that availability can change based on pharmacy licensing and provider decisions. Always confirm during checkout that your specific Florida zip code is covered.

Florida-Based Compounding Pharmacies

Florida is home to several compounding pharmacies that prepare GLP-1 medications. Some telehealth providers partner with Florida-based pharmacies to serve local patients, which can sometimes result in faster shipping.

When evaluating a provider, ask whether their pharmacy holds a Florida Special Sterile Compounding Permit and whether they use a 503A or 503B facility. 503B outsourcing facilities are FDA-registered and follow current Good Manufacturing Practices (cGMP), providing an additional layer of oversight.

What Florida Residents Should Know

BMI Requirements Apply

Regardless of state, GLP-1 medications require a prescription and are typically prescribed to patients with a BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related health condition such as hypertension, type 2 diabetes, or high cholesterol.

No State-Specific Restrictions

Unlike some states that have issued specific warnings about compounded GLP-1s or enacted additional restrictions, Florida has not taken any special regulatory action targeting these medications. The state applies its standard compounding pharmacy regulations.

Insurance Considerations

Most compounded GLP-1 medications are not covered by insurance, as insurance typically only covers FDA-approved products. Florida residents can use HSA or FSA funds for compounded medications in most cases, but should verify with their account administrator.

Red Flags to Watch For

While compounded GLP-1s are legal in Florida, not all providers are equally trustworthy. Watch for these warning signs:

• ⚠️ Providers that don't require a medical consultation or prescription
• ⚠️ Vague or undisclosed pharmacy sourcing
• ⚠️ Claims that compounded products are "FDA-approved" (they are not)
• ⚠️ Prices that seem too good to be true
• ⚠️ No clear information about LegitScript or PCAB certification

How to Get Started in Florida

If you're a Florida resident interested in compounded GLP-1 therapy, here's the typical process:

1. 1. Choose a telehealth provider – Use our comparison tool to evaluate pricing, pharmacy type, and certifications
2. 2. Complete a health questionnaire – You'll answer questions about your medical history, current medications, and weight-loss goals
3. 3. Have a provider consultation – A licensed Florida provider will review your information and may conduct a video or phone call
4. 4. Receive your prescription – If approved, your medication ships directly to your Florida address
5. 5. Follow up regularly – Most providers require monthly check-ins to monitor progress and adjust dosing

The Bottom Line

Florida is one of the most accessible states for compounded GLP-1 medications. The state's regulatory framework supports both local and out-of-state compounding pharmacies, and telehealth prescribing is well-established. Most major providers serve Florida without restrictions.

The key is choosing a reputable provider that works with properly licensed pharmacies and provides transparent information about their sourcing and certifications. Take time to verify credentials before making a purchase.